8I7T

The crystal structure of human abl1 kinase domain in complex with ABL1-B4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Tyrosine-protein kinase ABL1	polymer	272	31659.1	2	UniProt (P00519) Pfam (PF07714)	Homo sapiens (human)	Abelson murine leukemia viral oncogene homolog 1,Abelson tyrosine-protein kinase 1,Proto-oncogene c-Abl,p150
2	C, D (A, B)	[3-[5-[5-(dimethylcarbamoyl)pyridin-3-yl]-1H-pyrrolo[2,3-b]pyridin-3-yl]-4-methoxy-phenyl] ethanesulfonate	non-polymer		480.5	2	Chemie (6I5)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	63318.3
Non-Polymers*	Number of molecules	2
	Total formula weight	961.1
All*	Total formula weight	64279.3

*Water molecules are not included.