8I7S

The crystal structure of human abl1 kinase domain in complex with ABL1-B1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Tyrosine-protein kinase ABL1	polymer	272	31659.1	2	UniProt (P00519) Pfam (PF07714)	Homo sapiens (human)	Abelson murine leukemia viral oncogene homolog 1,Abelson tyrosine-protein kinase 1,Proto-oncogene c-Abl,p150
2	C, D (A, B)	5-[3-(2-methoxy-5-oxidanyl-phenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethyl-pyridine-3-carboxamide	non-polymer		388.4	2	Chemie (6CI)
3	E, F (A, B)	water	water		18.0	476	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	63318.3
Non-Polymers*	Number of molecules	2
	Total formula weight	776.8
All*	Total formula weight	64095.1

*Water molecules are not included.