8I7L
Crystal structure of indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with a novel inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Indoleamine 2,3-dioxygenase 1 | polymer | 403 | 45384.2 | 2 | UniProt (P14902) Pfam (PF01231) | Homo sapiens (human) | IDO-1,Indoleamine-pyrrole 2,3-dioxygenase |
| 2 | C (A) | THIOSULFATE | non-polymer | 112.1 | 1 | Chemie (THJ) | |||
| 3 | D, E (A, B) | 1-[3-[(4-chloranyl-2-fluoranyl-phenyl)carbamoylamino]-4-[cyclohexyl(2-methylpropyl)amino]phenyl]pyrrole-2-carboxylic acid | non-polymer | 527.0 | 2 | Chemie (OIH) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 90768.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1166.2 | |
| All* | Total formula weight | 91934.6 |
