8I79
Cryo-EM structure of KCTD7 in complex with Cullin3
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | F, A, D, G, I | BTB/POZ domain-containing protein KCTD7 | polymer | 297 | 34146.6 | 5 | UniProt (Q8BJK1) Pfam (PF02214) In PDB | Mus musculus (house mouse) | |
2 | B, C, E, H, J | Cullin-3 | polymer | 376 | 44146.4 | 5 | UniProt (Q13618) Pfam (PF00888) In PDB | Homo sapiens (human) | CUL-3 |
Sequence modifications
F, A, D, G, I: 1 - 289 (UniProt: Q8BJK1)
B, C, E, H, J: 22 - 388 (UniProt: Q13618)
PDB | External Database | Details |
---|---|---|
Asp -7 | - | expression tag |
Tyr -6 | - | expression tag |
Lys -5 | - | expression tag |
Asp -4 | - | expression tag |
Asp -3 | - | expression tag |
Asp -2 | - | expression tag |
Asp -1 | - | expression tag |
Lys 0 | - | expression tag |
Tyr 126 | His 126 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Met 13 | - | initiating methionine |
His 14 | - | expression tag |
His 15 | - | expression tag |
His 16 | - | expression tag |
His 17 | - | expression tag |
His 18 | - | expression tag |
His 19 | - | expression tag |
Gly 20 | - | expression tag |
Ser 21 | - | expression tag |
Arg 342 | Ile 342 | engineered mutation |
Asp 346 | Leu 346 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 10 |
Total formula weight | 391465.3 | |
All* | Total formula weight | 391465.3 |