8I5G
Structure of human Nav1.7 in complex with PF-05089771
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B | Sodium channel subunit beta-1 | polymer | 192 | 21977.2 | 1 | UniProt (Q07699) Pfam (PF07686) In PDB | Homo sapiens (human) | |
2 | C | Sodium channel subunit beta-2 | polymer | 215 | 24355.9 | 1 | UniProt (O60939) Pfam (PF07686) In PDB | Homo sapiens (human) | Nav1.7 beta2 subunit |
3 | A | Sodium channel protein type 9 subunit alpha | polymer | 1988 | 226620.0 | 1 | UniProt (Q15858) Pfam (PF00520) Pfam (PF11933) Pfam (PF06512) Pfam (PF08016) In PDB | Homo sapiens (human) | Neuroendocrine sodium channel,hNE-Na,Peripheral sodium channel 1,PN1,Sodium channel protein type IX subunit alpha,Voltage-gated sodium channel subunit alpha Nav1.7 |
4 | D, E, F | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
5 | B, A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
6 | A | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 2 | Chemie (Y01) | |||
7 | A | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en | non-polymer | 544.8 | 1 | Chemie (9Z9) | |||
8 | A | PF-05089771 | non-polymer | 500.4 | 1 | Chemie (T70) | |||
9 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
10 | A | 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 510.7 | 8 | Chemie (LPE) | |||
11 | A | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 787.1 | 5 | Chemie (PCW) | |||
12 | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 272953.1 | |
Branched | Number of molecules | 3 |
Total formula weight | 1273.2 | |
Non-Polymers* | Number of molecules | 23 |
Total formula weight | 11168.9 | |
All* | Total formula weight | 285395.2 |