8I5E
Crystal structure of HLA-A*11:01 in complex with KRAS peptide (VVGAGGVGK)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | MHC class I antigen (Fragment) | polymer | 274 | 31753.0 | 1 | UniProt (U5YJJ6) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (human) | |
| 2 | B (L) | Beta-2-microglobulin | polymer | 99 | 11748.2 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C (P) | KRAS-G12wt-9 | polymer | 9 | 743.9 | 1 | UniProt (P01116) | Homo sapiens | |
| 4 | D, E, F (H, L, P) | water | water | 18.0 | 161 | Chemie (HOH) |
Sequence modifications
H: 1 - 274 (UniProt: U5YJJ6)
| PDB | External Database | Details |
|---|---|---|
| Val 245 | Ala 269 | engineered mutation |
| Gln 253 | Glu 277 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 44245.0 | |
| All* | Total formula weight | 44245.0 |
