8I4X
Cryo-EM structure of 5-subunit Smc5/6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Structural maintenance of chromosomes protein 5 | polymer | 1069 | 123390.0 | 1 | UniProt (Q08204) Pfam (PF02463) | Saccharomyces cerevisiae S288C | |
| 2 | B (B) | Structural maintenance of chromosomes protein 6 | polymer | 1104 | 126889.4 | 1 | UniProt (Q12749) Pfam (PF13476) | Saccharomyces cerevisiae S288C | DNA repair protein RHC18,Rad18 homolog |
| 3 | C (C) | E3 SUMO-protein ligase MMS21 | polymer | 267 | 30388.3 | 1 | UniProt (P38632) Pfam (PF22326) Pfam (PF11789) | Saccharomyces cerevisiae S288C | E3 SUMO-protein transferase MMS21,Methyl methanesulfonate-sensitivity protein 21,Non-structural maintenance of chromosome element 2,Non-SMC element 2 |
| 4 | D (D) | Nse6 | polymer | 378 | 44498.2 | 1 | UniProt (P40026) Pfam (PF08691) | Saccharomyces cerevisiae S288C | |
| 5 | E (E) | Non-structural maintenance of chromosome element 5 | polymer | 556 | 64079.6 | 1 | UniProt (Q03718) Pfam (PF08691) | Saccharomyces cerevisiae S288C | Non-SMC element 5 |
Sequence modifications
A: 25 - 1093 (UniProt: Q08204)
B: 1 - 1104 (UniProt: Q12749)
| PDB | External Database | Details |
|---|---|---|
| Ala 824 | Met 824 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 464 | Leu 464 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 389245.6 | |
| All* | Total formula weight | 389245.6 |
