8I4I

The asymmetric structure of homodimeric E. coli TrpRS bound with tryptophanyl adenylate and L-tryptophan

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Tryptophan--tRNA ligase	polymer	340	38373.7	2	UniProt (P00954) Pfam (PF00579) In PDB	Escherichia coli K-12	Tryptophanyl-tRNA synthetase,TrpRS
2	A	TRYPTOPHAN	non-polymer		204.2	1	Chemie (TRP)
3	A, B	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4	B	TRYPTOPHANYL-5'AMP	non-polymer		533.4	1	Chemie (TYM)
5		water	water		18.0	246	Chemie (HOH)

Sequence modifications

A, B: 1 - 333 (UniProt: P00954)

PDB	External Database	Details
Arg 334	-	expression tag
His 335	-	expression tag
His 336	-	expression tag
His 337	-	expression tag
His 338	-	expression tag
His 339	-	expression tag
His 340	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	76747.5
Non-Polymers*	Number of molecules	4
	Total formula weight	929.8
All*	Total formula weight	77677.3

*Water molecules are not included.