8I4G

Omicron spike variant BQ.1.1 with n3130v-Fc

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (C)	n3130v-Fc	polymer	383	42016.8	1		Homo sapiens
2	B (A)	Spike glycoprotein	polymer	1294	143053.5	1	UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601)	Severe acute respiratory syndrome coronavirus 2	S glycoprotein,E2,Peplomer protein

Sequence modifications

A: 36 - 1214 (UniProt: P0DTC2)

PDB	External Database	Details
Met 1	-	initiating methionine
Pro 2	-	expression tag
Met 3	-	expression tag
Gly 4	-	expression tag
Ser 5	-	expression tag
Leu 6	-	expression tag
Gln 7	-	expression tag
Pro 8	-	expression tag
Leu 9	-	expression tag
Ala 10	-	expression tag
Thr 11	-	expression tag
Leu 12	-	expression tag
Tyr 13	-	expression tag
Leu 14	-	expression tag
Leu 15	-	expression tag
Gly 16	-	expression tag
Met 17	-	expression tag
Leu 18	-	expression tag
Val 19	-	expression tag
Ala 20	-	expression tag
Ser 21	-	expression tag
Val 22	-	expression tag
Leu 23	-	expression tag
Ala 24	-	expression tag
Gln 25	-	expression tag
Cys 26	-	expression tag
Val 27	-	expression tag
Asn 28	-	expression tag
Leu 29	-	expression tag
Ile 30	-	expression tag
Thr 31	-	expression tag
Arg 32	-	expression tag
Thr 33	-	expression tag
Gln 34	-	expression tag
Ser 35	-	expression tag
-	His 69	deletion
-	Val 70	deletion
Asp 148	Gly 142	variant
Gly 219	Val 213	variant
Asp 345	Gly 339	variant
Thr 352	Arg 346	variant
Phe 377	Ser 371	variant
Pro 379	Ser 373	variant
Phe 381	Ser 375	variant
Ala 382	Thr 376	variant
Asn 411	Asp 405	variant
Ser 414	Arg 408	variant
Asn 423	Lys 417	variant
Lys 446	Asn 440	variant
Thr 450	Lys 444	variant
Arg 458	Leu 452	variant
Lys 466	Asn 460	variant
Asn 483	Ser 477	variant
Lys 484	Thr 478	variant
Ala 490	Glu 484	variant
Val 492	Phe 486	variant
Arg 504	Gln 498	variant
Tyr 507	Asn 501	variant
His 511	Tyr 505	variant
Gly 620	Asp 614	variant
Tyr 661	His 655	variant
Lys 685	Asn 679	variant
His 687	Pro 681	conflict
Gly 688	Arg 682	engineered mutation
Ser 689	Arg 683	engineered mutation
Ser 691	Arg 685	engineered mutation
Lys 770	Asn 764	variant
Tyr 802	Asp 796	variant
His 960	Gln 954	variant
Lys 975	Asn 969	variant
Gly 1215	-	expression tag
Ser 1216	-	expression tag
Gly 1217	-	expression tag
Tyr 1218	-	expression tag
Ile 1219	-	expression tag
Pro 1220	-	expression tag
Glu 1221	-	expression tag
Ala 1222	-	expression tag
Pro 1223	-	expression tag
Arg 1224	-	expression tag
Asp 1225	-	expression tag
Gly 1226	-	expression tag
Gln 1227	-	expression tag
Ala 1228	-	expression tag
Tyr 1229	-	expression tag
Val 1230	-	expression tag
Arg 1231	-	expression tag
Lys 1232	-	expression tag
Asp 1233	-	expression tag
Gly 1234	-	expression tag
Glu 1235	-	expression tag
Trp 1236	-	expression tag
Val 1237	-	expression tag
Phe 1238	-	expression tag
Leu 1239	-	expression tag
Ser 1240	-	expression tag
Thr 1241	-	expression tag
Phe 1242	-	expression tag
Leu 1243	-	expression tag
Ser 1244	-	expression tag
Gly 1245	-	expression tag
Leu 1246	-	expression tag
Glu 1247	-	expression tag
Val 1248	-	expression tag
Leu 1249	-	expression tag
Phe 1250	-	expression tag
Gln 1251	-	expression tag
Gly 1252	-	expression tag
Pro 1253	-	expression tag
Gly 1254	-	expression tag
Gly 1255	-	expression tag
Trp 1256	-	expression tag
Ser 1257	-	expression tag
His 1258	-	expression tag
Pro 1259	-	expression tag
Gln 1260	-	expression tag
Phe 1261	-	expression tag
Glu 1262	-	expression tag
Lys 1263	-	expression tag
Gly 1264	-	expression tag
Gly 1265	-	expression tag
Gly 1266	-	expression tag
Ser 1267	-	expression tag
Gly 1268	-	expression tag
Gly 1269	-	expression tag
Gly 1270	-	expression tag
Ser 1271	-	expression tag
Gly 1272	-	expression tag
Gly 1273	-	expression tag
Ser 1274	-	expression tag
Ala 1275	-	expression tag
Trp 1276	-	expression tag
Ser 1277	-	expression tag
His 1278	-	expression tag
Pro 1279	-	expression tag
Gln 1280	-	expression tag
Phe 1281	-	expression tag
Glu 1282	-	expression tag
Lys 1283	-	expression tag
Gly 1284	-	expression tag
Gly 1285	-	expression tag
Ser 1286	-	expression tag
His 1287	-	expression tag
His 1288	-	expression tag
His 1289	-	expression tag
His 1290	-	expression tag
His 1291	-	expression tag
His 1292	-	expression tag
His 1293	-	expression tag
His 1294	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	185070.3
All*	Total formula weight	185070.3

*Water molecules are not included.