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8I2J

E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Tryptophan--tRNA ligasepolymer34038373.72UniProt (P00954)
Pfam (PF00579)
Escherichia coli K-12Tryptophanyl-tRNA synthetase,TrpRS
2C
(A)
1-(4-methoxyphenyl)ethanonenon-polymer150.21Chemie (O9F)
3D
(B)
TRYPTOPHANYL-5'AMPnon-polymer533.41Chemie (TYM)
4E
(B)
SULFATE IONnon-polymer96.11Chemie (SO4)
5F, G
(A, B)
waterwater18.072Chemie (HOH)
Sequence modifications
A, B: 1 - 333 (UniProt: P00954)
PDBExternal DatabaseDetails
Arg 334-expression tag
His 335-expression tag
His 336-expression tag
His 337-expression tag
His 338-expression tag
His 339-expression tag
His 340-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight76747.5
Non-Polymers*Number of molecules3
Total formula weight779.7
All*Total formula weight77527.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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