8I0Z

Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human C5a anaphylatoxin chemotactic receptor 1, C5aR1 (Local refine)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Beta-arrestin-2	polymer	420	47217.7	3	UniProt (P32120) Pfam (PF00339) Pfam (PF02752) In PDB	Bos taurus (cattle)	Arrestin beta-2,Arrestin-3
2	D, H, M	Fab30 Heavy Chain	polymer	237	25512.4	3		Mus musculus
3	E, L, N	Fab30 Light Chain	polymer	215	23435.1	3		Mus musculus
4	G, U, V	C5a anaphylatoxin chemotactic receptor 1	polymer	20	2698.3	3	UniProt (P21730) In PDB	Homo sapiens	C5a anaphylatoxin chemotactic receptor,C5a-R,C5aR

Sequence modifications

A, B, C: 1 - 420 (UniProt: P32120)

PDB	External Database	Details
Gly 17	Cys 17	engineered mutation
Val 60	Cys 60	engineered mutation
Cys 69	Leu 69	engineered mutation
Ser 126	Cys 126	engineered mutation
Leu 141	Cys 141	engineered mutation
Val 151	Cys 151	engineered mutation
Val 243	Cys 243	engineered mutation
Val 252	Cys 252	engineered mutation
Ser 270	Cys 270	engineered mutation
Phe 278	Leu 278	engineered mutation
Ala 280	Ser 280	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	296590.3
All*	Total formula weight	296590.3

*Water molecules are not included.