Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Pre-mRNA-processing-splicing factor 8 | polymer | 2335 | 273974.3 | 1 | UniProt (Q6P2Q9) Pfam (PF08082) Pfam (PF08083) Pfam (PF10598) Pfam (PF10597) Pfam (PF10596) Pfam (PF12134) Pfam (PF01398) Pfam (PF08084) In PDB | Homo sapiens (human) | 220 kDa U5 snRNP-specific protein,PRP8 homolog,Splicing factor Prp8,p220 |
| 2 | B | U5 snRNA | polymer | 117 | 37254.9 | 1 | GenBank (20330981) | Homo sapiens (human) | |
| 3 | C | 116 kDa U5 small nuclear ribonucleoprotein component | polymer | 972 | 109560.6 | 1 | UniProt (Q15029) Pfam (PF16004) Pfam (PF00009) Pfam (PF03144) Pfam (PF14492) Pfam (PF03764) Pfam (PF00679) In PDB | Homo sapiens (human) | SNU114,Elongation factor Tu GTP-binding domain-containing protein 2,SNU114 homolog,hSNU114,U5 snRNP-specific protein,116 kDa,U5-116 kDa |
| 4 | D | U5 small nuclear ribonucleoprotein 200 kDa helicase | polymer | 2136 | 244823.4 | 1 | UniProt (O75643) Pfam (PF21188) Pfam (PF18149) Pfam (PF00270) Pfam (PF00271) Pfam (PF02889) In PDB | Homo sapiens (human) | Activating signal cointegrator 1 complex subunit 3-like 1,BRR2 homolog,U5 snRNP-specific 200 kDa protein,U5-200KD |
| 5 | E | U5 small nuclear ribonucleoprotein 40 kDa protein | polymer | 357 | 39359.5 | 1 | UniProt (Q96DI7) Pfam (PF00400) In PDB | Homo sapiens (human) | U5-40K,38 kDa-splicing factor,Prp8-binding protein,hPRP8BP,U5 snRNP-specific 40 kDa protein,WD repeat-containing protein 57 |
| 6 | F | U6 snRNA | polymer | 107 | 34404.4 | 1 | Homo sapiens | ||
| 7 | G | pre-mRNA | polymer | 220 | 70435.4 | 1 | unidentified adenovirus | ||
| 8 | H | U2 snRNA | polymer | 188 | 60186.4 | 1 | GenBank (340097) | Homo sapiens (human) | |
| 9 | I | Pre-mRNA-splicing factor SYF1 | polymer | 855 | 100148.7 | 1 | UniProt (Q9HCS7) Pfam (PF13181) In PDB | Homo sapiens (human) | Protein HCNP,XPA-binding protein 2 |
| 10 | J | Crooked neck-like protein 1 | polymer | 848 | 100610.0 | 1 | UniProt (Q9BZJ0) Pfam (PF02184) In PDB | Homo sapiens (human) | Crooked neck homolog,hCrn |
| 11 | K | RING finger protein 113A | polymer | 343 | 38847.2 | 1 | UniProt (O15541) Pfam (PF00642) Pfam (PF13920) In PDB | Homo sapiens (human) | Zinc finger protein 183 |
| 12 | L | Cell division cycle 5-like protein | polymer | 802 | 92406.9 | 1 | UniProt (Q99459) Pfam (PF13921) Pfam (PF11831) In PDB | Homo sapiens (human) | Cdc5-like protein,Pombe cdc5-related protein |
| 13 | N | Protein BUD31 homolog | polymer | 144 | 17032.8 | 1 | UniProt (P41223) Pfam (PF01125) In PDB | Homo sapiens (human) | Protein EDG-2,Protein G10 homolog |
| 14 | O | Pre-mRNA-splicing factor RBM22 | polymer | 420 | 46959.6 | 1 | UniProt (Q9NW64) Pfam (PF21369) Pfam (PF00076) In PDB | Homo sapiens (human) | RNA-binding motif protein 22,Zinc finger CCCH domain-containing protein 16 |
| 15 | P | Spliceosome-associated protein CWC15 homolog | polymer | 229 | 26674.4 | 1 | UniProt (Q9P013) Pfam (PF04889) In PDB | Homo sapiens (human) | |
| 16 | Q | RNA helicase aquarius | polymer | 1485 | 171502.5 | 1 | UniProt (O60306) Pfam (PF16399) Pfam (PF21143) Pfam (PF21144) Pfam (PF13086) Pfam (PF13087) In PDB | Homo sapiens (human) | Intron-binding protein of 160 kDa,IBP160 |
| 17 | R | SNW domain-containing protein 1 | polymer | 536 | 61690.7 | 1 | UniProt (Q13573) Pfam (PF02731) In PDB | Homo sapiens (human) | Nuclear protein SkiP,Nuclear receptor coactivator NCoA-62,Ski-interacting protein |
| 18 | S | Peptidyl-prolyl cis-trans isomerase-like 1 | polymer | 166 | 18257.8 | 1 | UniProt (Q9Y3C6) Pfam (PF00160) In PDB | Homo sapiens (human) | PPIase,Rotamase PPIL1 |
| 19 | T | Pleiotropic regulator 1 | polymer | 514 | 57280.8 | 1 | UniProt (O43660) Pfam (PF00400) In PDB | Homo sapiens (human) | |
| 20 | U | Serine/arginine repetitive matrix protein 2 | polymer | 2752 | 300255.3 | 1 | UniProt (Q9UQ35) Pfam (PF08312) In PDB | Homo sapiens (human) | 300 kDa nuclear matrix antigen,Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa,Ser/Arg-related nuclear matrix protein of 300 kDa,Splicing coactivator subunit SRm300,Tax-responsive enhancer element-binding protein 803,TaxREB803 |
| 21 | V | Pre-mRNA-splicing factor CWC22 homolog | polymer | 908 | 105646.6 | 1 | UniProt (Q9HCG8) Pfam (PF02854) Pfam (PF02847) In PDB | Homo sapiens (human) | Nucampholin homolog,fSAPb |
| 22 | X | Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 | polymer | 1041 | 119443.6 | 1 | UniProt (O60231) Pfam (PF00270) Pfam (PF00271) Pfam (PF04408) Pfam (PF21010) Pfam (PF07717) In PDB | Homo sapiens (human) | ATP-dependent RNA helicase #3,DEAH-box protein 16 |
| 23 | Y | Peptidyl-prolyl cis-trans isomerase-like 4 | polymer | 492 | 57324.2 | 1 | UniProt (Q8WUA2) Pfam (PF00160) Pfam (PF00076) In PDB | Homo sapiens (human) | PPIase,Cyclophilin-like protein PPIL4,Rotamase PPIL4 |
| 24 | 1 | Splicing factor 3B subunit 1 | polymer | 1304 | 146024.9 | 1 | UniProt (O75533) Pfam (PF08920) Pfam (PF22646) In PDB | Homo sapiens (human) | Pre-mRNA-splicing factor SF3b 155 kDa subunit,SF3b155,Spliceosome-associated protein 155,SAP 155 |
| 25 | 3 | Splicing factor 3B subunit 3 | polymer | 1217 | 135718.8 | 1 | UniProt (Q15393) Pfam (PF10433) Pfam (PF03178) In PDB | Homo sapiens (human) | Pre-mRNA-splicing factor SF3b 130 kDa subunit,SF3b130,STAF130,Spliceosome-associated protein 130,SAP 130 |
| 26 | p | U2 small nuclear ribonucleoprotein B'' | polymer | 225 | 25524.4 | 1 | UniProt (P08579) Pfam (PF00076) In PDB | Homo sapiens (human) | U2 snRNP B'' |
| 27 | w | Splicing factor 3A subunit 3 | polymer | 501 | 58934.8 | 1 | UniProt (Q12874) Pfam (PF12108) Pfam (PF16837) Pfam (PF13297) Pfam (PF11931) In PDB | Homo sapiens (human) | SF3a60,Spliceosome-associated protein 61,SAP 61 |
| 28 | 2 | Splicing factor 3B subunit 2 | polymer | 895 | 100377.8 | 1 | UniProt (Q13435) Pfam (PF02037) Pfam (PF04037) Pfam (PF04046) In PDB | Homo sapiens (human) | Pre-mRNA-splicing factor SF3b 145 kDa subunit,SF3b145,Spliceosome-associated protein 145,SAP 145 |
| 29 | 4 | Splicing factor 3B subunit 4 | polymer | 424 | 44436.6 | 1 | UniProt (Q15427) Pfam (PF00076) In PDB | Homo sapiens (human) | Pre-mRNA-splicing factor SF3b 49 kDa subunit,Spliceosome-associated protein 49,SAP 49 |
| 30 | 7 | PHD finger-like domain-containing protein 5A | polymer | 110 | 12427.5 | 1 | UniProt (Q7RTV0) Pfam (PF03660) In PDB | Homo sapiens (human) | PHD finger-like domain protein 5A,Splicing factor 3B-associated 14 kDa protein,SF3b14b |
| 31 | 5 | Splicing factor 3B subunit 5 | polymer | 86 | 10149.4 | 1 | UniProt (Q9BWJ5) Pfam (PF07189) In PDB | Homo sapiens (human) | SF3b5,Pre-mRNA-splicing factor SF3b 10 kDa subunit |
| 32 | y | Peptidyl-prolyl cis-trans isomerase E | polymer | 301 | 33475.8 | 1 | UniProt (Q9UNP9) Pfam (PF00076) Pfam (PF00160) In PDB | Homo sapiens (human) | PPIase E,Cyclophilin E,Cyclophilin-33,Rotamase E |
| 33 | v | Splicing factor 3A subunit 2 | polymer | 464 | 49327.4 | 1 | UniProt (Q15428) Pfam (PF12874) Pfam (PF16835) In PDB | Homo sapiens (human) | SF3a66,Spliceosome-associated protein 62,SAP 62 |
| 34 | u | Splicing factor 3A subunit 1 | polymer | 793 | 88991.1 | 1 | UniProt (Q15459) Pfam (PF01805) Pfam (PF12230) Pfam (PF00240) In PDB | Homo sapiens (human) | SF3a120,Spliceosome-associated protein 114,SAP 114 |
| 35 | 9 | RING-type E3 ubiquitin-protein ligase PPIL2 | polymer | 520 | 58910.4 | 1 | UniProt (Q13356) Pfam (PF00160) In PDB | Homo sapiens (human) | Probable inactive peptidyl-prolyl cis-trans isomerase-like 2,PPIase,Rotamase PPIL2 |
| 36 | a, m | Small nuclear ribonucleoprotein-associated proteins B and B' | polymer | 240 | 24642.1 | 2 | UniProt (P14678) Pfam (PF01423) In PDB | Homo sapiens (human) | SmB,snRNP-B,Sm protein B/B',SmB/B' |
| 37 | b, n | Small nuclear ribonucleoprotein Sm D1 | polymer | 119 | 13310.7 | 2 | UniProt (P62314) Pfam (PF01423) In PDB | Homo sapiens (human) | Sm-D1,Sm-D autoantigen,snRNP core protein D1 |
| 38 | c, h | Small nuclear ribonucleoprotein Sm D2 | polymer | 118 | 13551.9 | 2 | UniProt (P62316) Pfam (PF01423) In PDB | Homo sapiens (human) | Sm-D2,snRNP core protein D2 |
| 39 | d, i | Small nuclear ribonucleoprotein F | polymer | 86 | 9734.2 | 2 | UniProt (P62306) Pfam (PF01423) In PDB | Homo sapiens (human) | snRNP-F,Sm protein F,SmF |
| 40 | e, j | Small nuclear ribonucleoprotein E | polymer | 92 | 10817.6 | 2 | UniProt (P62304) Pfam (PF01423) In PDB | Homo sapiens (human) | snRNP-E,Sm protein E,SmE |
| 41 | f, k | Small nuclear ribonucleoprotein G | polymer | 76 | 8508.1 | 2 | UniProt (P62308) Pfam (PF01423) In PDB | Homo sapiens (human) | snRNP-G,Sm protein G,SmG |
| 42 | g, l | Small nuclear ribonucleoprotein Sm D3 | polymer | 126 | 13940.3 | 2 | UniProt (P62318) Pfam (PF01423) In PDB | Homo sapiens (human) | Sm-D3,snRNP core protein D3 |
| 43 | o | U2 small nuclear ribonucleoprotein A' | polymer | 255 | 28456.6 | 1 | UniProt (P09661) Pfam (PF14580) In PDB | Homo sapiens (human) | U2-A',U2 snRNP A' |
| 44 | A | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 1 | Chemie (IHP) | |||
| 45 | C | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 46 | C, F | MAGNESIUM ION | non-polymer | 24.3 | 7 | Chemie (MG) | |||
| 47 | K, N, 7 | ZINC ION | non-polymer | 65.4 | 7 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 50 |
| Total formula weight | 3165845.2 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1811.2 | |
| All* | Total formula weight | 3167656.4 |
