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8I0R

The cryo-EM structure of human Bact-I complex

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Pre-mRNA-processing-splicing factor 8polymer2335273974.31UniProt (Q6P2Q9)Homo sapiens (human)PRP8 homolog,Splicing factor Prp8
2B
(B)
U5 snRNApolymer11737254.91GenBank (20330981)Homo sapiens (human)
3C
(C)
116 kDa U5 small nuclear ribonucleoprotein componentpolymer972109560.61UniProt (Q15029)Homo sapiens (human)SNU114 homolog,hSNU114
4D
(D)
U5 small nuclear ribonucleoprotein 200 kDa helicasepolymer2136244823.41UniProt (O75643)Homo sapiens (human)BRR2 homolog
5E
(E)
U5 small nuclear ribonucleoprotein 40 kDa proteinpolymer35739359.51UniProt (Q96DI7)Homo sapiens (human)U5-40K,U5 snRNP-specific 40 kDa protein
6F
(F)
U6 snRNApolymer10734404.41Homo sapiens
7G
(G)
pre-mRNApolymer22070435.41unidentified adenovirus
8H
(H)
U2 snRNApolymer18860186.41GenBank (340097)Homo sapiens (human)
9I
(I)
Pre-mRNA-splicing factor SYF1polymer855100148.71UniProt (Q9HCS7)Homo sapiens (human)
10J
(J)
Crooked neck-like protein 1polymer848100610.01UniProt (Q9BZJ0)Homo sapiens (human)SYF3
11K
(K)
RING finger protein 113Apolymer34338847.21UniProt (O15541)Homo sapiens (human)
12L
(L)
Cell division cycle 5-like proteinpolymer80292406.91UniProt (Q99459)Homo sapiens (human)Cdc5-like protein,Pombe cdc5-related protein
13M
(N)
Protein BUD31 homologpolymer14417032.81UniProt (P41223)Homo sapiens (human)Protein G10 homolog
14N
(O)
Pre-mRNA-splicing factor RBM22polymer42046959.61UniProt (Q9NW64)Homo sapiens (human)RNA-binding motif protein 22
15O
(P)
Spliceosome-associated protein CWC15 homologpolymer22926674.41UniProt (Q9P013)Homo sapiens (human)
16P
(Q)
RNA helicase aquariuspolymer1485171502.51UniProt (O60306)Homo sapiens (human)
17Q
(R)
SNW domain-containing protein 1polymer53661610.71UniProt (Q13573)Homo sapiens (human)
18R
(S)
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16polymer1041119443.61UniProt (O60231)Homo sapiens (human)ATP-dependent RNA helicase #3,DEAH-box protein 16
19S
(T)
Pleiotropic regulator 1polymer51457280.81UniProt (O43660)Homo sapiens (human)
20T
(U)
Serine/arginine repetitive matrix protein 2polymer2752300255.31UniProt (Q9UQ35)Homo sapiens (human)Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa,Ser/Arg-related nuclear matrix protein of 300 kDa
21U
(V)
Pre-mRNA-splicing factor CWC22 homologpolymer908105646.61UniProt (Q9HCG8)Homo sapiens (human)
22V
(W)
Unknown polymerpolymer12210541.01Homo sapiens
23W
(X)
Smad nuclear-interacting protein 1polymer39645880.71UniProt (Q8TAD8)Homo sapiens (human)FHA domain-containing protein SNIP1
24X
(Y)
RNA-binding motif protein, X-linked 2polymer32237426.01UniProt (Q9Y388)Homo sapiens (human)
25Y
(Z)
BUD13 homologpolymer61970669.21UniProt (Q9BRD0)Homo sapiens (human)
26Z
(1)
Splicing factor 3B subunit 1polymer1304146104.91UniProt (O75533)Homo sapiens (human)Pre-mRNA-splicing factor SF3b 155 kDa subunit,SF3b155,Spliceosome-associated protein 155,SAP 155
27AA
(3)
Splicing factor 3B subunit 3polymer1217135718.81UniProt (Q15393)Homo sapiens (human)Pre-mRNA-splicing factor SF3b 130 kDa subunit,SF3b130
28BA
(p)
U2 small nuclear ribonucleoprotein B''polymer22525524.41UniProt (P08579)Homo sapiens (human)U2-B",U2,U2 snRNP B''
29CA
(w)
Splicing factor 3A subunit 3polymer50158934.81UniProt (Q12874)Homo sapiens (human)SF3a60
30DA
(u)
Splicing factor 3A subunit 1polymer79388991.11UniProt (Q15459)Homo sapiens (human)SF3a120
31EA
(2)
Splicing factor 3B subunit 2polymer895100377.81UniProt (Q13435)Homo sapiens (human)Pre-mRNA-splicing factor SF3b 145 kDa subunit,SF3b145
32FA
(4)
Splicing factor 3B subunit 4polymer42444436.61UniProt (Q15427)Homo sapiens (human)Pre-mRNA-splicing factor SF3b 49 kDa subunit
33GA
(6)
Splicing factor 3B subunit 6polymer12514606.91UniProt (Q9Y3B4)Homo sapiens (human)SF3b 14 kDa subunit,SF3B14a,Splicing factor 3b subunit 6 14kDa
34HA
(7)
PHD finger-like domain-containing protein 5Apolymer11012427.51UniProt (Q7RTV0)Homo sapiens (human)PHD finger-like domain protein 5A
35IA
(5)
Splicing factor 3B subunit 5polymer8610149.41UniProt (Q9BWJ5)Homo sapiens (human)SF3b5
36JA
(9)
RING-type E3 ubiquitin-protein ligase PPIL2polymer52058910.41UniProt (Q13356)Homo sapiens (human)Probable inactive peptidyl-prolyl cis-trans isomerase-like 2,PPIase,Rotamase PPIL2
37KA
(8)
Serine/arginine repetitive matrix protein 1polymer904102600.51UniProt (Q8IYB3)Homo sapiens (human)Ser/Arg-related nuclear matrix protein
38LA
(y)
Peptidyl-prolyl cis-trans isomerase Epolymer30133475.81UniProt (Q9UNP9)Homo sapiens (human)PPIase E,Cyclophilin E,Rotamase E
39MA
(v)
Splicing factor 3A subunit 2polymer46449327.41UniProt (Q15428)Homo sapiens (human)SF3a66
40NA
(o)
U2 small nuclear ribonucleoprotein A'polymer25528456.61UniProt (P09661)Homo sapiens (human)U2-A',U2 snRNP A'
41OA, YA
(h, c)
Small nuclear ribonucleoprotein Sm D2polymer11813551.92UniProt (P62316)Homo sapiens (human)Sm-D2,snRNP core protein D2
42PA, ZA
(i, d)
Small nuclear ribonucleoprotein Fpolymer869734.22UniProt (P62306)Homo sapiens (human)snRNP-F,Sm protein F,SmF
43QA, WA
(m, a)
Small nuclear ribonucleoprotein-associated proteins B and B'polymer24024642.12UniProt (P14678)Homo sapiens (human)SmB,snRNP-B,Sm protein B/B',SmB/B'
44CB, RA
(l, g)
Small nuclear ribonucleoprotein Sm D3polymer12613940.32UniProt (P62318)Homo sapiens (human)SmD3,Sm-D3,snRNP core protein D3
45BB, SA
(k, f)
Small nuclear ribonucleoprotein Gpolymer768508.12UniProt (P62308)Homo sapiens (human)snRNP-G,Sm protein G,SmG
46AB, TA
(j, e)
Small nuclear ribonucleoprotein Epolymer9210817.62UniProt (P62304)Homo sapiens (human)snRNP-E,Sm protein E,SmE
47UA, XA
(n, b)
Small nuclear ribonucleoprotein Sm D1polymer11913310.72UniProt (P62314)Homo sapiens (human)Sm-D1,Sm-D autoantigen,snRNP core protein D1
48VA
(z)
Peptidyl-prolyl cis-trans isomerase CWC27 homologpolymer47253941.21UniProt (Q6UX04)Homo sapiens (human)PPIase CWC27
49DB
(A)
INOSITOL HEXAKISPHOSPHATEnon-polymer660.01Chemie (IHP)
50EB
(C)
GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.21Chemie (GTP)
51FB, GB, HB, IB, JB...
(C, F)
MAGNESIUM IONnon-polymer24.36Chemie (MG)
52LB, MB, NB, OB, PB...
(K, N, 7)
ZINC IONnon-polymer65.47Chemie (ZN)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains55
Total formula weight3425928.8
Non-Polymers*Number of molecules15
Total formula weight1786.9
All*Total formula weight3427715.7
*Water molecules are not included.

238582

PDB entries from 2025-07-09

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