8HYR

Crystal structure of human KARS apo

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Lysine--tRNA ligase	polymer	520	60197.2	2	UniProt (Q15046) Pfam (PF01336) Pfam (PF00152)	Homo sapiens (human)	Lysyl-tRNA synthetase,LysRS
2	C, D (A, B)	water	water		18.0	183	Chemie (HOH)

Sequence modifications

A, B: 70 - 580 (UniProt: Q15046)

PDB	External Database	Details
Met 69	-	initiating methionine
Leu 581	-	expression tag
Glu 582	-	expression tag
His 583	-	expression tag
His 584	-	expression tag
His 585	-	expression tag
His 586	-	expression tag
His 587	-	expression tag
His 588	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	120394.4
All*	Total formula weight	120394.4

*Water molecules are not included.