8HY5

Structure of D-amino acid oxidase mutant R38H

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	D-amino-acid oxidase	polymer	370	41962.6	2	UniProt (P14920) Pfam (PF01266) In PDB	Homo sapiens (human)	DAAO,DAMOX,DAO
2	A, B	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	2	Chemie (FAD)
3	A, B	BENZOIC ACID	non-polymer		122.1	2	Chemie (BEZ)
4	A	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
5	B	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
6		water	water		18.0	155	Chemie (HOH)

Sequence modifications

A, B: 1 - 347 (UniProt: P14920)

PDB	External Database	Details
Met -22	-	initiating methionine
Gly -21	-	expression tag
Ser -20	-	expression tag
Ser -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Ser -12	-	expression tag
Ser -11	-	expression tag
Gly -10	-	expression tag
Leu -9	-	expression tag
Val -8	-	expression tag
Pro -7	-	expression tag
Arg -6	-	expression tag
Gly -5	-	expression tag
Ser -4	-	expression tag
His -3	-	expression tag
Met -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag
His 38	Arg 38	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	83925.1
Non-Polymers*	Number of molecules	6
	Total formula weight	1900.4
All*	Total formula weight	85825.5

*Water molecules are not included.