8HXX
Cryo-EM structure of the histone deacetylase complex Rpd3S
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (K) | Transcriptional regulatory protein SIN3 | polymer | 1536 | 175047.3 | 1 | UniProt (P22579) Pfam (PF02671) Pfam (PF08295) Pfam (PF16879) | Saccharomyces cerevisiae (baker's yeast) | |
| 2 | B (L) | Histone deacetylase RPD3 | polymer | 433 | 48962.0 | 1 | UniProt (P32561) Pfam (PF00850) | Saccharomyces cerevisiae (baker's yeast) | Transcriptional regulatory protein RPD3 |
| 3 | C, E (M, O) | Chromatin modification-related protein EAF3 | polymer | 401 | 45266.4 | 2 | UniProt (A0A8H4F719) Pfam (PF05712) Pfam (PF11717) Pfam (PF22732) UniProt (by SIFTS) (Q12432) | Saccharomyces cerevisiae (baker's yeast) | |
| 4 | D, F (N, P) | RCO1 isoform 1 | polymer | 684 | 78951.3 | 2 | UniProt (A0A8H4BXB0) Pfam (PF00628) UniProt (by SIFTS) (Q04779) | Saccharomyces cerevisiae (baker's yeast) | |
| 5 | G (E) | Histone H3 | polymer | 135 | 15332.0 | 1 | UniProt (A0A310TTQ1) Pfam (PF00125) UniProt (by SIFTS) (P84233) | Xenopus laevis (African clawed frog) | |
| 6 | H, I, J, K, L... (L, N, P) | ZINC ION | non-polymer | 65.4 | 7 | Chemie (ZN) |
Sequence modifications
E: 1 - 135 (UniProt: A0A310TTQ1)
| PDB | External Database | Details |
|---|---|---|
| Ala 110 | Cys 111 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 487776.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 457.9 | |
| All* | Total formula weight | 488234.5 |
