8HWS
The complex structure of Omicron BA.4 RBD with BD604, S309, and S304
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Spike protein S2' | polymer | 196 | 22136.0 | 1 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | |
| 2 | B (H) | BD-604 Fab Heavy chain | polymer | 229 | 24121.1 | 1 | Homo sapiens | ||
| 3 | C (L) | BD-604 Fab Light chain | polymer | 215 | 23391.9 | 1 | Homo sapiens | ||
| 4 | D (D) | S304 Fab Heavy Chain | polymer | 231 | 24613.4 | 1 | Homo sapiens | ||
| 5 | E (E) | S304 Fab Light Chain | polymer | 216 | 23458.0 | 1 | Homo sapiens | ||
| 6 | F (I) | S309 Fab Heavy Chain | polymer | 239 | 25586.6 | 1 | Homo sapiens | ||
| 7 | G (J) | S309 Fab Light Chain | polymer | 215 | 23291.8 | 1 | Homo sapiens | ||
| 8 | H (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) |
Sequence modifications
A: 333 - 528 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Asp 339 | Gly 339 | variant |
| Phe 371 | Ser 371 | variant |
| Pro 373 | Ser 373 | variant |
| Phe 375 | Ser 375 | variant |
| Ala 376 | Thr 376 | variant |
| Asn 405 | Asp 405 | variant |
| Ser 408 | Arg 408 | variant |
| Asn 417 | Lys 417 | variant |
| Lys 440 | Asn 440 | variant |
| Arg 452 | Leu 452 | variant |
| Asn 477 | Ser 477 | variant |
| Lys 478 | Thr 478 | variant |
| Ala 484 | Glu 484 | variant |
| Val 486 | Phe 486 | variant |
| Arg 498 | Gln 498 | variant |
| Tyr 501 | Asn 501 | variant |
| His 505 | Tyr 505 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 166598.8 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 570.5 | |
| All* | Total formula weight | 167169.3 |
