8HV2
Crystal structure of EGFR_wt in complex with covalently bound fragment 4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Epidermal growth factor receptor | polymer | 331 | 37632.5 | 1 | UniProt (P00533) Pfam (PF07714) In PDB | Homo sapiens (human) | Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1 |
| 2 | A | ~{N}-pyridin-2-ylprop-2-enamide | non-polymer | 148.2 | 1 | Chemie (MWU) | |||
| 3 | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence modifications
A: 694 - 1022 (UniProt: P00533)
| PDB | External Database | Details |
|---|---|---|
| Gly 692 | - | expression tag |
| Ser 693 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37632.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 148.2 | |
| All* | Total formula weight | 37780.6 |
