8HUL
X-ray structure of human PPAR delta ligand binding domain-lanifibranor co-crystals obtained by co-crystallization
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Peroxisome proliferator-activated receptor delta | polymer | 276 | 31527.6 | 2 | UniProt (Q03181) Pfam (PF00104) In PDB | Homo sapiens (human) | PPAR-delta,NUCI,Nuclear hormone receptor 1,NUC1,Nuclear receptor subfamily 1 group C member 2,Peroxisome proliferator-activated receptor beta,PPAR-beta |
| 2 | A, B | 4-[1-(1,3-benzothiazol-6-ylsulfonyl)-5-chloro-indol-2-yl]butanoic acid | non-polymer | 434.9 | 2 | Chemie (BJB) |
Sequence modifications
A, B: 170 - 441 (UniProt: Q03181)
| PDB | External Database | Details |
|---|---|---|
| Gly 166 | - | expression tag |
| Ser 167 | - | expression tag |
| His 168 | - | expression tag |
| Met 169 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63055.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 869.8 | |
| All* | Total formula weight | 63925.1 |
