8HTT
Cryo-EM structure of human TMEM87A, gluconate-bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Transmembrane protein 87A,EGFP | polymer | 864 | 97965.6 | 1 | UniProt (Q8NBN3) UniProt (A0A6M5E0N3) Pfam (PF21901) Pfam (PF06814) | Homo sapiens (human) | |
| 2 | B, C (A, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | D (D) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 4 | E (B) | D-gluconic acid | non-polymer | 196.2 | 1 | Chemie (GCO) |
Sequence modifications
B: 1 - 555 (UniProt: Q8NBN3)
B: 587 - 824 (UniProt: A0A6M5E0N3)
| PDB | External Database | Details |
|---|---|---|
| Leu 556 | - | linker |
| Lys 557 | - | linker |
| Glu 558 | - | linker |
| Asn 559 | - | linker |
| Leu 560 | - | linker |
| Tyr 561 | - | linker |
| Phe 562 | - | linker |
| Gln 563 | - | linker |
| Gly 564 | - | linker |
| Gly 565 | - | linker |
| Thr 566 | - | linker |
| Leu 567 | - | linker |
| Glu 568 | - | linker |
| Val 569 | - | linker |
| Leu 570 | - | linker |
| Phe 571 | - | linker |
| Gln 572 | - | linker |
| Gly 573 | - | linker |
| Pro 574 | - | linker |
| Asn 575 | - | linker |
| Pro 576 | - | linker |
| Ala 577 | - | linker |
| Phe 578 | - | linker |
| Leu 579 | - | linker |
| Tyr 580 | - | linker |
| Lys 581 | - | linker |
| Val 582 | - | linker |
| Val 583 | - | linker |
| Asp 584 | - | linker |
| Pro 585 | - | linker |
| Val 586 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Gln 770 | His 185 | conflict |
| Glu 825 | - | expression tag |
| Phe 826 | - | expression tag |
| Leu 827 | - | expression tag |
| Val 828 | - | expression tag |
| Pro 829 | - | expression tag |
| Arg 830 | - | expression tag |
| Gly 831 | - | expression tag |
| Ser 832 | - | expression tag |
| Ser 833 | - | expression tag |
| Arg 834 | - | expression tag |
| Ser 835 | - | expression tag |
| Ala 836 | - | expression tag |
| Trp 837 | - | expression tag |
| Ser 838 | - | expression tag |
| His 839 | - | expression tag |
| Pro 840 | - | expression tag |
| Gln 841 | - | expression tag |
| Phe 842 | - | expression tag |
| Glu 843 | - | expression tag |
| Lys 844 | - | expression tag |
| Gly 845 | - | expression tag |
| Gly 846 | - | expression tag |
| Gly 847 | - | expression tag |
| Ser 848 | - | expression tag |
| Gly 849 | - | expression tag |
| Gly 850 | - | expression tag |
| Gly 851 | - | expression tag |
| Ser 852 | - | expression tag |
| Gly 853 | - | expression tag |
| Gly 854 | - | expression tag |
| Ser 855 | - | expression tag |
| Ala 856 | - | expression tag |
| Trp 857 | - | expression tag |
| Ser 858 | - | expression tag |
| His 859 | - | expression tag |
| Pro 860 | - | expression tag |
| Gln 861 | - | expression tag |
| Phe 862 | - | expression tag |
| Glu 863 | - | expression tag |
| Lys 864 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 97965.6 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1435.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 196.2 | |
| All* | Total formula weight | 99597.1 |
