8HSL
Thermus thermophilus RNA polymerase bound with an inverted Rho hexamer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | G, H | DNA-directed RNA polymerase subunit alpha | polymer | 315 | 35056.2 | 2 | UniProt (Q5SHR6) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) In PDB | Thermus thermophilus HB8 | RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha |
| 2 | I | DNA-directed RNA polymerase subunit beta | polymer | 1119 | 125436.5 | 1 | UniProt (Q8RQE9) Pfam (PF10385) Pfam (PF00562) Pfam (PF04560) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) In PDB | Thermus thermophilus HB8 | RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta |
| 3 | J | DNA-directed RNA polymerase subunit beta' | polymer | 1532 | 171994.4 | 1 | UniProt (Q8RQE8) Pfam (PF04997) Pfam (PF21668) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) In PDB | Thermus thermophilus HB8 | RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta' |
| 4 | K | DNA-directed RNA polymerase subunit omega | polymer | 99 | 11533.3 | 1 | UniProt (Q8RQE7) Pfam (PF01192) In PDB | Thermus thermophilus HB8 | RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega |
| 5 | A, B, C, D, E... | Transcription termination factor Rho | polymer | 428 | 47996.3 | 6 | UniProt (Q5SJE9) Pfam (PF07498) Pfam (PF07497) Pfam (PF00006) In PDB | Thermus thermophilus HB8 | |
| 6 | J | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 7 | E, F, J, A, B... | MAGNESIUM ION | non-polymer | 24.3 | 7 | Chemie (MG) | |||
| 8 | F, A, B, C, D... | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 6 | Chemie (ADP) | |||
| 9 | E, F, A, B, C... | BERYLLIUM TRIFLUORIDE ION | non-polymer | 66.0 | 6 | Chemie (BEF) |
Sequence modifications
J: 1 - 1524 (UniProt: Q8RQE8)
A, B, C, D, E, F: 1 - 426 (UniProt: Q5SJE9)
| PDB | External Database | Details |
|---|---|---|
| Asp 1525 | - | expression tag |
| Tyr 1526 | - | expression tag |
| Lys 1527 | - | expression tag |
| Asp 1528 | - | expression tag |
| Asp 1529 | - | expression tag |
| Asp 1530 | - | expression tag |
| Asp 1531 | - | expression tag |
| Lys 1532 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 667054.2 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 3194.8 | |
| All* | Total formula weight | 670249.0 |
