8HSG
Thermus thermophilus RNA polymerase elongation complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (G, H) | DNA-directed RNA polymerase subunit alpha | polymer | 315 | 35056.2 | 2 | UniProt (Q5SHR6) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) | Thermus thermophilus HB8 | RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha |
| 2 | C (I) | DNA-directed RNA polymerase subunit beta | polymer | 1119 | 125436.5 | 1 | UniProt (Q8RQE9) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) Pfam (PF04560) | Thermus thermophilus HB8 | RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta |
| 3 | D (J) | DNA-directed RNA polymerase subunit beta' | polymer | 1532 | 171994.4 | 1 | UniProt (Q8RQE8) Pfam (PF04997) Pfam (PF21668) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) | Thermus thermophilus HB8 | RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta' |
| 4 | E (K) | DNA-directed RNA polymerase subunit omega | polymer | 99 | 11491.2 | 1 | UniProt (Q8RQE7) Pfam (PF01192) | Thermus thermophilus HB8 | RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega |
| 5 | F (T) | DNA (37-MER) | polymer | 184 | 57785.0 | 1 | DNA molecule | ||
| 6 | G (R) | RNA (5'-R(P*CP*CP*AP*CP*AP*UP*CP*CP*AP*CP*CP*U)-3') | polymer | 125 | 39054.0 | 1 | synthetic construct | ||
| 7 | H (N) | DNA (27-MER) | polymer | 180 | 54576.8 | 1 | synthetic construct | ||
| 8 | I (J) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 9 | J (J) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence modifications
J: 1 - 1524 (UniProt: Q8RQE8)
K: 1 - 99 (UniProt: Q8RQE7)
| PDB | External Database | Details |
|---|---|---|
| Asp 1525 | - | expression tag |
| Tyr 1526 | - | expression tag |
| Lys 1527 | - | expression tag |
| Asp 1528 | - | expression tag |
| Asp 1529 | - | expression tag |
| Asp 1530 | - | expression tag |
| Asp 1531 | - | expression tag |
| Lys 1532 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 95 | Val 95 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 530450.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 89.7 | |
| All* | Total formula weight | 530540.0 |
