8HPO
Cryo-EM structure of a SIN3/HDAC complex from budding yeast
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | K | Transcriptional regulatory protein UME1 | polymer | 460 | 51075.6 | 1 | UniProt (Q03010) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | WD repeat-containing transcriptional modulator 3 |
| 2 | D | Transcriptional regulatory protein SDS3 | polymer | 327 | 37765.3 | 1 | UniProt (P40505) Pfam (PF08598) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Suppressor of defective silencing protein 3 |
| 3 | F | Histone deacetylase RPD3 | polymer | 433 | 49361.8 | 1 | UniProt (P32561) Pfam (PF00850) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Transcriptional regulatory protein RPD3 |
| 4 | G | Histone deacetylase RPD3 | polymer | 433 | 48962.0 | 1 | UniProt (P32561) Pfam (PF00850) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Transcriptional regulatory protein RPD3 |
| 5 | I | Transcriptional regulatory protein SAP30 | polymer | 201 | 23144.2 | 1 | UniProt (P38429) Pfam (PF13867) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | |
| 6 | A, B | Transcriptional regulatory protein SIN3 | polymer | 1536 | 175047.3 | 2 | UniProt (P22579) Pfam (PF02671) Pfam (PF08295) Pfam (PF16879) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | |
| 7 | H | Transcriptional regulatory protein DEP1 | polymer | 405 | 47035.7 | 1 | UniProt (P31385) Pfam (PF08598) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | |
| 8 | C | Transcriptional regulatory protein PHO23 | polymer | 330 | 37081.4 | 1 | UniProt (P50947) Pfam (PF12998) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | |
| 9 | E | Transcriptional regulatory protein RXT2 | polymer | 430 | 48844.0 | 1 | UniProt (P38255) Pfam (PF08595) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | |
| 10 | J | Transcriptional regulatory protein RXT3 | polymer | 294 | 33851.5 | 1 | UniProt (Q07458) Pfam (PF08642) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | |
| 11 | F | PHOSPHOTHREONINE | non-polymer | 199.1 | 1 | Chemie (TPO) | |||
| 12 | F, G | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 13 | F, G | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 727216.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 486.3 | |
| All* | Total formula weight | 727702.4 |
