8HJ2
GPR21 wt with G15 complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 340 | 37416.9 | 1 | UniProt (P62873) Pfam (PF00400) In PDB | Homo sapiens (human) | Transducin beta chain 1,G protein beta subunit |
2 | G | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 96 | 10366.8 | 1 | UniProt (P59768) Pfam (PF00631) In PDB | Homo sapiens (human) | G gamma-I |
3 | N | Nb35 | polymer | 149 | 16054.2 | 1 | Homo sapiens | ||
4 | R | Probable G-protein coupled receptor 21 | polymer | 349 | 39546.0 | 1 | UniProt (Q99679) Pfam (PF00001) In PDB | Homo sapiens (human) | |
5 | A | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | polymer | 249 | 28768.4 | 1 | UniProt (P63092) Pfam (PF00503) In PDB | Homo sapiens (human) | Adenylate cyclase-stimulating G alpha protein |
Sequence modifications
G: 1 - 71 (UniProt: P59768)
A: 5 - 195 (UniProt: P63092)
A: 204 - 371 (UniProt: P63092)
PDB | External Database | Details |
---|---|---|
His -24 | - | expression tag |
His -23 | - | expression tag |
His -22 | - | expression tag |
His -21 | - | expression tag |
His -20 | - | expression tag |
His -19 | - | expression tag |
Gly -18 | - | expression tag |
Gly -17 | - | expression tag |
Gly -16 | - | expression tag |
Ser -15 | - | expression tag |
Asp -14 | - | expression tag |
Ser -13 | - | expression tag |
Leu -12 | - | expression tag |
Glu -11 | - | expression tag |
Phe -10 | - | expression tag |
Ile -9 | - | expression tag |
Ala -8 | - | expression tag |
Ser -7 | - | expression tag |
Lys -6 | - | expression tag |
Leu -5 | - | expression tag |
Ala -4 | - | expression tag |
Gly -3 | - | expression tag |
Gly -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Ser 68 | Cys 68 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Asp 49 | Gly 49 | engineered mutation |
Asn 50 | Glu 50 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 196 | - | linker |
Gly 197 | - | linker |
Ser 198 | - | linker |
Gly 199 | - | linker |
Gly 200 | - | linker |
Ser 201 | - | linker |
Gly 202 | - | linker |
Gly 203 | - | linker |
Asp 249 | Ala 249 | engineered mutation |
Asp 252 | Ser 252 | engineered mutation |
- | Asn 254 | deletion |
- | Met 255 | deletion |
- | Val 256 | deletion |
- | Ile 257 | deletion |
- | Arg 258 | deletion |
- | Glu 259 | deletion |
- | Asp 260 | deletion |
- | Asn 261 | deletion |
- | Gln 262 | deletion |
- | Thr 263 | deletion |
Ala 362 | Ile 372 | engineered mutation |
Ile 365 | Val 375 | engineered mutation |
Ser 372 | - | expression tag |
Val 373 | - | expression tag |
Leu 374 | - | expression tag |
Ala 375 | - | expression tag |
Arg 376 | - | expression tag |
Tyr 377 | - | expression tag |
Leu 378 | - | expression tag |
Asp 379 | - | expression tag |
Glu 380 | - | expression tag |
Ile 381 | - | expression tag |
Asn 382 | - | expression tag |
Leu 383 | - | expression tag |
Leu 384 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 132152.3 | |
All* | Total formula weight | 132152.3 |