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8HJ1

GPR21(wt) and Gs complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AGuanine nucleotide-binding protein G(s) subunit alpha isoforms shortpolymer25930167.11UniProt (P63092)
Pfam (PF00503)
In PDB
Homo sapiens (human)Adenylate cyclase-stimulating G alpha protein
2BGuanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1polymer34037416.91UniProt (P62873)
Pfam (PF00400)
In PDB
Homo sapiens (human)Transducin beta chain 1,G protein beta subunit
3GGuanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2polymer9610366.81UniProt (P59768)
Pfam (PF00631)
In PDB
Homo sapiens (human)G gamma-I
4NNb35polymer14916054.21Homo sapiens
5RProbable G-protein coupled receptor 21polymer34939546.01UniProt (Q99679)
Pfam (PF00001)
In PDB
Homo sapiens (human)
Sequence modifications
A: 5 - 195 (UniProt: P63092)
PDBExternal DatabaseDetails
Asp 49Gly 49engineered mutation
Asn 50Glu 50engineered mutation
A: 204 - 394 (UniProt: P63092)
PDBExternal DatabaseDetails
Gly 196-linker
Gly 197-linker
Ser 198-linker
Gly 199-linker
Gly 200-linker
Ser 201-linker
Gly 202-linker
Gly 203-linker
Asp 249Ala 249engineered mutation
Asp 252Ser 252engineered mutation
Ala 372Ile 372engineered mutation
Ile 375Val 375engineered mutation
G: 1 - 71 (UniProt: P59768)
PDBExternal DatabaseDetails
His -24-expression tag
His -23-expression tag
His -22-expression tag
His -21-expression tag
His -20-expression tag
His -19-expression tag
Gly -18-expression tag
Gly -17-expression tag
Gly -16-expression tag
Ser -15-expression tag
Asp -14-expression tag
Ser -13-expression tag
Leu -12-expression tag
Glu -11-expression tag
Phe -10-expression tag
Ile -9-expression tag
Ala -8-expression tag
Ser -7-expression tag
Lys -6-expression tag
Leu -5-expression tag
Ala -4-expression tag
Gly -3-expression tag
Gly -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Ser 68Cys 68engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight133551.0
All*Total formula weight133551.0
*Water molecules are not included.

224004

PDB entries from 2024-08-21

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