8HIK
The TPP-bound BRIL-SLC19A1/Fab/Nb ternary complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | BRIL-SLC19A1 chimera | polymer | 683 | 75110.3 | 1 | UniProt (P0ABE7) UniProt (P41440) Pfam (PF07361) Pfam (PF01770) | Escherichia coli | |
| 2 | B (H) | Anti-BRIL Fab heavy chain | polymer | 260 | 27759.2 | 1 | Homo sapiens (Human) | ||
| 3 | C (N) | Anti-Fab nanobody | polymer | 153 | 16673.6 | 1 | Lama glama | ||
| 4 | D (L) | Anti-BRIL Fab light chain | polymer | 235 | 25575.6 | 1 | Homo sapiens (Human) | ||
| 5 | E (A) | THIAMINE DIPHOSPHATE | non-polymer | 425.3 | 1 | Chemie (TPP) |
Sequence modifications
A: -82 - 22 (UniProt: P0ABE7)
A: 24 - 591 (UniProt: P41440)
| PDB | External Database | Details |
|---|---|---|
| Gly -88 | - | expression tag |
| Pro -87 | - | expression tag |
| Ser -86 | - | expression tag |
| Arg -85 | - | expression tag |
| Ala -84 | - | expression tag |
| Thr -83 | - | expression tag |
| Trp -76 | Met 29 | conflict |
| Ile 19 | His 124 | conflict |
| Leu 23 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ser 592 | - | expression tag |
| Asn 593 | - | expression tag |
| Ser 594 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 145118.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 425.3 | |
| All* | Total formula weight | 145544.0 |
