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8HHM

Cryo-EM structure of the Cas12m2-crRNA-target DNA ternary complex intermediate state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
RNA (56-MER)polymer5718623.11Mycolicibacterium mucogenicum
2B
(C)
DNA (36-MER)polymer3610976.11Mycolicibacterium mucogenicum
3C
(D)
DNA (36-MER)polymer3611180.21Mycolicibacterium mucogenicum
4D
(A)
Cas12m2polymer59866457.01UniProt (by SIFTS) (P0DXB1)Mycolicibacterium mucogenicum
5E
(B)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
PubChem (888)
6F
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight107236.4
Non-Polymers*Number of molecules2
Total formula weight89.7
All*Total formula weight107326.1
*Water molecules are not included.

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PDB entries from 2026-03-25

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