8HGC

Crystal structure of the CYP199A4 mutant F182T in complex with 4-methoxybenzoic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Cytochrome P450	polymer	420	45800.8	1	UniProt (Q2IU02) Pfam (PF00067) In PDB	Rhodopseudomonas palustris HaA2
2	A	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	1	Chemie (HEM)
3	A	4-METHOXYBENZOIC ACID	non-polymer		152.1	1	Chemie (ANN)
4	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5	A	ACETATE ION	non-polymer		59.0	3	Chemie (ACT)
6		water	water		18.0	429	Chemie (HOH)

Sequence modifications

A: 0 - 409 (UniProt: Q2IU02)

PDB	External Database	Details
Met -2	-	initiating methionine
Gly -1	-	expression tag
Thr 182	Phe 183	engineered mutation
Leu 410	-	expression tag
Glu 411	-	expression tag
His 412	-	expression tag
His 413	-	expression tag
His 414	-	expression tag
His 415	-	expression tag
His 416	-	expression tag
His 417	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	45800.8
Non-Polymers*	Number of molecules	6
	Total formula weight	1037.9
All*	Total formula weight	46838.6

*Water molecules are not included.