8HGC
Crystal structure of the CYP199A4 mutant F182T in complex with 4-methoxybenzoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cytochrome P450 | polymer | 420 | 45800.8 | 1 | UniProt (Q2IU02) Pfam (PF00067) | Rhodopseudomonas palustris HaA2 | |
| 2 | B (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | C (A) | 4-METHOXYBENZOIC ACID | non-polymer | 152.1 | 1 | Chemie (ANN) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E, F, G (A) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 6 | H (A) | water | water | 18.0 | 429 | Chemie (HOH) |
Sequence modifications
A: 0 - 409 (UniProt: Q2IU02)
| PDB | External Database | Details |
|---|---|---|
| Met -2 | - | initiating methionine |
| Gly -1 | - | expression tag |
| Thr 182 | Phe 183 | engineered mutation |
| Leu 410 | - | expression tag |
| Glu 411 | - | expression tag |
| His 412 | - | expression tag |
| His 413 | - | expression tag |
| His 414 | - | expression tag |
| His 415 | - | expression tag |
| His 416 | - | expression tag |
| His 417 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45800.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1037.9 | |
| All* | Total formula weight | 46838.6 |
