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8HEO

Crystal structure of SIAH1 SBD bound to Axin2 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
E3 ubiquitin-protein ligase SIAH1polymer19421823.02UniProt (Q8IUQ4)
Pfam (PF21361)
Pfam (PF03145)
Homo sapiens (human)RING-type E3 ubiquitin transferase SIAH1,Seven in absentia homolog 1,Siah-1,Siah-1a
2C
(G)
Peptide from Axin-2polymer212340.71UniProt (Q9Y2T1)Homo sapiens (human)Axin-like protein,Axil,Axis inhibition protein 2,Conductin
3D, E, F, G
(A, B)
ZINC IONnon-polymer65.44Chemie (ZN)
4H, I
(A, B)
waterwater18.020Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight45986.7
Non-Polymers*Number of molecules4
Total formula weight261.6
All*Total formula weight46248.3
*Water molecules are not included.

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PDB entries from 2025-12-17

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