8HEJ
Crystal structure of Transthyretin in complex with a covalent inhibitor trans-styrylpyrazole
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Transthyretin | polymer | 114 | 12503.0 | 2 | UniProt (P02766) Pfam (PF00576) In PDB | Homo sapiens (human) | ATTR,Prealbumin,TBPA |
2 | A, B | 2,6-dibromo-4-[(E)-2-(3,5-dimethyl-1H-pyrazol-4-yl)ethenyl]phenol | non-polymer | 372.1 | 2 | Chemie (XHF) | |||
3 | A, B | 2,4,6-trifluorobenzaldehyde | non-polymer | 160.1 | 2 | Chemie (XHB) | |||
4 | water | water | 18.0 | 149 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 25005.9 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1064.3 | |
All* | Total formula weight | 26070.2 |