8HEC
SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab in the class 2 conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Spike glycoprotein | polymer | 1208 | 133753.3 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
| 2 | D, F, H (D, F, H) | rabbit antibody 9H1 light chain | polymer | 110 | 11654.8 | 3 | Oryctolagus cuniculus | ||
| 3 | E, G, I (E, G, I) | rabbit antibody 9H1 heavy chain | polymer | 117 | 12556.1 | 3 | Oryctolagus cuniculus | ||
| 4 | J, K, L, M, N... (O, J, K, L, M...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 17 | In PDB GlyTouCan (G42666HT) | |||
| 5 | AA, AB, BA, CA, DA... (A, C, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 27 | Chemie (NAG) |
Sequence modifications
A, B, C: 1 - 1208 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 682 | Arg 682 | engineered mutation |
| Ser 683 | Arg 683 | engineered mutation |
| Ser 685 | Arg 685 | engineered mutation |
| Pro 986 | Lys 986 | engineered mutation |
| Pro 987 | Val 987 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 473892.4 | |
| Branched | Number of molecules | 17 |
| Total formula weight | 7214.8 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 5972.6 | |
| All* | Total formula weight | 487079.9 |
