8HEB
SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab in the class 1 conformation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Spike glycoprotein | polymer | 1208 | 133753.3 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
2 | D, F, H | rabbit antibody 9H1 light chain | polymer | 110 | 11654.8 | 3 | Oryctolagus cuniculus | ||
3 | E, G, I | rabbit antibody 9H1 heavy chain | polymer | 117 | 12556.1 | 3 | Oryctolagus cuniculus | ||
4 | a, O, J, K, L... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 18 | In PDB GlyTouCan (G42666HT) | |||
5 | C, A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 27 | Chemie (NAG) |
Sequence modifications
A, B, C: 1 - 1208 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Gly 682 | Arg 682 | engineered mutation |
Ser 683 | Arg 683 | engineered mutation |
Ser 685 | Arg 685 | engineered mutation |
Pro 986 | Lys 986 | engineered mutation |
Pro 987 | Val 987 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 9 |
Total formula weight | 473892.4 | |
Branched | Number of molecules | 18 |
Total formula weight | 7639.2 | |
Non-Polymers* | Number of molecules | 27 |
Total formula weight | 5972.6 | |
All* | Total formula weight | 487504.3 |