8H9Y
Crystal structure of voltage-gated sodium channel NavAb N49K/L176Q mutant in calcium ion condition
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ion transport protein | polymer | 271 | 31412.3 | 1 | UniProt (A8EVM5) Pfam (PF00520) | Aliarcobacter butzleri | VOLTAGE-GATED SODIUM CHANNEL |
| 2 | B, C (A) | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 2 | Chemie (LMT) | |||
| 3 | D (A) | CHAPSO | non-polymer | 631.9 | 1 | Chemie (1N7) PubChem (122146) PubChem (3253739) PubChem (9895487) PubChem (16402373) PubChem (44119969) PubChem (44660322) PubChem (23636791) PubChem (23639399) PubChem (50987332) PubChem (71305076) PubChem (90479263) PubChem (96545191) PubChem (53393747) PubChem (124745618) PubChem (124901558) PubChem (124905421) PubChem (125027410) PubChem (10009199) PubChem (144605089) PubChem (71464051) PubChem (96327541) PubChem (96327542) PubChem (96327543) PubChem (96327544) PubChem (96545192) PubChem (102565431) PubChem (121392376) PubChem (122130148) PubChem (124901556) PubChem (124901561) PubChem (124901563) PubChem (124905422) PubChem (125027411) PubChem (129537355) PubChem (129537356) PubChem (145705472) PubChem (146030291) PubChem (146159852) | |||
| 4 | E, F, G, H, I... (A) | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 678.9 | 8 | Chemie (PX4) PubChem (26198) PubChem (87505) PubChem (5313082) | |||
| 5 | M, N (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) PubChem (271) | |||
| 6 | O (A) | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A: 1001 - 1267 (UniProt: A8EVM5)
| PDB | External Database | Details |
|---|---|---|
| Gly 997 | - | expression tag |
| Ser 998 | - | expression tag |
| Gly 999 | - | expression tag |
| Ser 1000 | - | expression tag |
| Lys 1049 | Asn 49 | engineered mutation |
| Gln 1176 | Leu 176 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31412.3 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 7164.8 | |
| All* | Total formula weight | 38577.0 |
