8H9X
Crystal structure of voltage-gated sodium channel NavAb N49K/L176Q mutant in sodium ion condition
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ion transport protein | polymer | 271 | 31412.3 | 1 | UniProt (A8EVM5) Pfam (PF00520) Pfam (PF08016) | Aliarcobacter butzleri | VOLTAGE-GATED SODIUM CHANNEL |
| 2 | B, C (A) | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 2 | Chemie (LMT) | |||
| 3 | D (A) | CHAPSO | non-polymer | 631.9 | 1 | Chemie (1N7) | |||
| 4 | E, F, G, H, I... (A) | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 678.9 | 8 | Chemie (PX4) | |||
| 5 | M, N (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 6 | O (A) | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
A: 1001 - 1267 (UniProt: A8EVM5)
| PDB | External Database | Details |
|---|---|---|
| Gly 997 | - | expression tag |
| Ser 998 | - | expression tag |
| Gly 999 | - | expression tag |
| Ser 1000 | - | expression tag |
| Lys 1049 | Asn 49 | engineered mutation |
| Gln 1176 | Leu 176 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31412.3 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 7130.6 | |
| All* | Total formula weight | 38542.9 |
