8H8P

Crystal structure of thiomorpholine-carboxylate dehydrogenase from Candida parapsilosis.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A, C, D	Thiomorpholine-carboxylate dehydrogenase	polymer	371	41465.3	4	UniProt (G8BA04) Pfam (PF02423) In PDB	Candida parapsilosis
2	C, B, D, A	1,2-ETHANEDIOL	non-polymer		62.1	22	Chemie (EDO)
3	B, A	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
4	C, B, A	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
5	C, A	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
6		water	water		18.0	51	Chemie (HOH)

Sequence modifications

B, A, C, D: 1 - 351 (UniProt: G8BA04)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Leu 199	Ser 199	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	165861.1
Non-Polymers*	Number of molecules	32
	Total formula weight	1647.9
All*	Total formula weight	167509.0

*Water molecules are not included.