8H0W
RNA polymerase II transcribing a chromatosome (type II)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA-directed RNA polymerase subunit | polymer | 1743 | 194107.4 | 1 | UniProt (C4R4Y0) Pfam (PF04997) Pfam (PF05001) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) Pfam (PF04992) Pfam (PF04990) | Komagataella phaffii | |
| 2 | B (B) | DNA-directed RNA polymerase subunit beta | polymer | 1227 | 139746.1 | 1 | UniProt (C4QZQ7) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) | Komagataella phaffii | |
| 3 | C (C) | RNA polymerase II third largest subunit B44, part of central core | polymer | 304 | 34216.3 | 1 | UniProt (C4R7L2) Pfam (PF01193) Pfam (PF01000) | Komagataella phaffii | |
| 4 | D (D) | RNA polymerase II subunit B32 | polymer | 186 | 20623.0 | 1 | UniProt (C4R2U9) Pfam (PF03874) | Komagataella phaffii | |
| 5 | E (E) | DNA-directed RNA polymerases I, II, and III subunit RPABC1 | polymer | 214 | 24962.7 | 1 | UniProt (C4R3P8) Pfam (PF03871) Pfam (PF01191) | Komagataella phaffii | |
| 6 | F (F) | RNA polymerase subunit ABC23, common to RNA polymerases I, II, and III | polymer | 155 | 17803.6 | 1 | UniProt (C4R1V1) Pfam (PF01192) | Komagataella phaffii | |
| 7 | G (G) | RNA polymerase II subunit | polymer | 171 | 18802.6 | 1 | UniProt (C4R9A1) Pfam (PF03876) Pfam (PF00575) | Komagataella phaffii | |
| 8 | H (H) | DNA-directed RNA polymerases I, II, and III subunit RPABC3 | polymer | 145 | 16249.2 | 1 | UniProt (C4R273) Pfam (PF03870) | Komagataella phaffii | |
| 9 | I (I) | DNA-directed RNA polymerase subunit | polymer | 115 | 13612.3 | 1 | UniProt (F2QPE6) Pfam (PF02150) Pfam (PF01096) | Komagataella phaffii | |
| 10 | J (J) | RNA polymerase subunit ABC10-beta, common to RNA polymerases I, II, and III | polymer | 72 | 8554.1 | 1 | UniProt (C4R009) Pfam (PF01194) | Komagataella phaffii | |
| 11 | K (K) | RNA polymerase II subunit B12.5 | polymer | 118 | 13832.9 | 1 | UniProt (C4R3Z5) Pfam (PF13656) | Komagataella phaffii | |
| 12 | L (L) | RNA polymerase subunit ABC10-alpha | polymer | 72 | 7862.0 | 1 | UniProt (F2QMI1) Pfam (PF03604) | Komagataella phaffii | |
| 13 | M (P) | RNA (5'-R(P*CP*AP*AP*UP*AP*GP*GP*AP*GP*CP*UP*UP*AP*C)-3') | polymer | 14 | 4470.7 | 1 | synthetic construct | ||
| 14 | N (T) | DNA (261-MER) | polymer | 261 | 80851.6 | 1 | synthetic construct | ||
| 15 | O (N) | DNA (261-MER) | polymer | 261 | 80329.1 | 1 | synthetic construct | ||
| 16 | P, T (a, e) | Histone H3.1 | polymer | 139 | 15719.4 | 2 | UniProt (P68431) Pfam (PF00125) | Homo sapiens (human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
| 17 | Q, U (b, f) | Histone H4 | polymer | 106 | 11676.7 | 2 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (human) | |
| 18 | R, V (c, g) | Histone H2A type 1-B/E | polymer | 133 | 14447.8 | 2 | UniProt (P04908) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (human) | Histone H2A.2,Histone H2A/a,Histone H2A/m |
| 19 | S, W (d, h) | Histone H2B type 1-J | polymer | 129 | 14217.5 | 2 | UniProt (P06899) Pfam (PF00125) | Homo sapiens (human) | Histone H2B.1,Histone H2B.r,H2B/r |
| 20 | X (u) | Histone H1.2 | polymer | 219 | 22156.8 | 1 | UniProt (P16403) Pfam (PF00538) | Homo sapiens (human) | Histone H1c,Histone H1d,Histone H1s-1 |
| 21 | BA, CA, DA, EA, FA... (B, C, I, J, L...) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 22 | AA (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence modifications
a, e: 1 - 135 (UniProt: P68431)
b, f: 0 - 102 (UniProt: P62805)
c, g: 0 - 129 (UniProt: P04908)
d, h: -3 - 122 (UniProt: P06899)
u: 1 - 213 (UniProt: P16403)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Ser -5 | - | expression tag |
| His -4 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 214 | - | expression tag |
| Glu 215 | - | expression tag |
| Val 216 | - | expression tag |
| Leu 217 | - | expression tag |
| Phe 218 | - | expression tag |
| Gln 219 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 24 |
| Total formula weight | 810303.4 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 547.6 | |
| All* | Total formula weight | 810851.0 |
