8H0P
Structure of the NMB30-NMBR and Gq complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | L | NMB30 | polymer | 10 | 1134.3 | 1 | Pfam (PF02044) UniProt (by SIFTS) (P08949) In PDB | Homo sapiens | |
| 2 | R | Neuromedin-B receptor | polymer | 390 | 43491.8 | 1 | UniProt (P28336) Pfam (PF00001) In PDB | Homo sapiens (human) | NMB-R,Epididymis tissue protein Li 185a,Neuromedin-B-preferring bombesin receptor |
| 3 | A | G-alpha q | polymer | 361 | 41724.4 | 1 | Pfam (PF00503) UniProt (by SIFTS) (P63096) UniProt (by SIFTS) (P63092) In PDB | Homo sapiens | |
| 4 | B | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 343 | 37771.4 | 1 | UniProt (P62873) Pfam (PF00400) In PDB | Homo sapiens (human) | Transducin beta chain 1 |
| 5 | E | scFv16 | polymer | 247 | 26277.3 | 1 | Mus musculus | ||
| 6 | G | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) In PDB | Homo sapiens (human) | G gamma-I |
Sequence modifications
R: 1 - 390 (UniProt: P28336)
B: 7 - 345 (UniProt: P62873)
| PDB | External Database | Details |
|---|---|---|
| Gln 134 | Leu 134 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 3 | - | expression tag |
| Leu 4 | - | expression tag |
| Leu 5 | - | expression tag |
| Gln 6 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 158260.3 | |
| All* | Total formula weight | 158260.3 |
