8GXP
Complex structure of RORgama with betulinic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nuclear receptor ROR-gamma | polymer | 269 | 31238.1 | 1 | UniProt (P51449) Pfam (PF00104) | Homo sapiens (Human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
| 2 | B (A) | Betulinic acid | non-polymer | 456.7 | 1 | Chemie (06L) | |||
| 3 | C (A) | water | water | 18.0 | 49 | Chemie (HOH) |
Sequence modifications
A: 265 - 507 (UniProt: P51449)
| PDB | External Database | Details |
|---|---|---|
| Glu 258 | - | expression tag |
| Asn 259 | - | expression tag |
| Leu 260 | - | expression tag |
| Tyr 261 | - | expression tag |
| Phe 262 | - | expression tag |
| Gln 263 | - | expression tag |
| Gly 264 | - | expression tag |
| Gly 508 | - | expression tag |
| Gly 509 | - | expression tag |
| Ser 552 | - | expression tag |
| Gly 553 | - | expression tag |
| Lys 554 | - | expression tag |
| Glu 555 | - | expression tag |
| Lys 556 | - | expression tag |
| His 557 | - | expression tag |
| Lys 558 | - | expression tag |
| Ile 559 | - | expression tag |
| Leu 560 | - | expression tag |
| His 561 | - | expression tag |
| Arg 562 | - | expression tag |
| Leu 563 | - | expression tag |
| Leu 564 | - | expression tag |
| Gln 565 | - | expression tag |
| Asp 566 | - | expression tag |
| Ser 567 | - | expression tag |
| Ser 568 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31238.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 456.7 | |
| All* | Total formula weight | 31694.8 |
