8GX2

The crystal structure of human CtsL in complex with 14c

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Procathepsin L	polymer	333	37605.1	2	UniProt (P07711) Pfam (PF08246) Pfam (PF00112)	Homo sapiens (human)	Cathepsin L1,Major excreted protein,MEP
2	C, E, F (A, B)	DIMETHYL SULFOXIDE	non-polymer		78.1	3	Chemie (DMS)
3	D, G (A, B)	N-[(2S)-3-cyclohexyl-1-[[(2S,3S)-4-(cyclopropylamino)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]butan-2-yl]amino]-1-oxidanylidene-propan-2-yl]-1-benzofuran-2-carboxamide	non-polymer		552.7	2	Chemie (KJ0)
4	H, I (A, B)	water	water		18.0	363	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	75210.1
Non-Polymers*	Number of molecules	5
	Total formula weight	1339.7
All*	Total formula weight	76549.9

*Water molecules are not included.