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8GWH

PTPN21 PTP domain C1108S mutant in complex with SRC pTyr530 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein phosphatase non-receptor type 21polymer29934664.51UniProt (Q16825)
Pfam (PF00102)
Homo sapiens (human)Protein-tyrosine phosphatase D1
2B
(E)
SRC pTyr530 peptidepolymer5743.71UniProt (by SIFTS) (P12931)Homo sapiens
3C, D
(A, E)
waterwater18.0142Chemie (HOH)
Sequence modifications
A: 876 - 1174 (UniProt: Q16825)
PDBExternal DatabaseDetails
Ser 1108Cys 1108engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight35408.1
All*Total formula weight35408.1
*Water molecules are not included.

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PDB entries from 2026-03-11

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