8GW3

Crystal structure of human TAK1 kinase domain fused with TAB1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Mitogen-activated protein kinase kinase kinase 7, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1	polymer	326	36740.2	4	UniProt (O43318) UniProt (Q15750) Pfam (PF07714)	Homo sapiens (human)	Transforming growth factor-beta-activated kinase 1,TGF-beta-activated kinase 1,Mitogen-activated protein kinase kinase kinase 7-interacting protein 1,TGF-beta-activated kinase 1-binding protein 1,TAK1-binding protein 1
2	E, F, G, H (A, B, C, D)	water	water		18.0	419	Chemie (HOH)

Sequence modifications

A, B, C, D: 15 - 303 (UniProt: O43318)
A, B, C, D: 468 - 504 (UniProt: Q15750)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	146960.8
All*	Total formula weight	146960.8

*Water molecules are not included.