8GUT
Cryo-EM structure of LEI-CB2-Gi complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40415.0 | 1 | UniProt (P63096) Pfam (PF00503) In PDB | Homo sapiens (human) | Adenylate cyclase-inhibiting G alpha protein |
| 2 | B | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 340 | 37416.9 | 1 | UniProt (P62873) Pfam (PF00400) In PDB | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C | Guanine nucleotide-binding protein subunit gamma | polymer | 71 | 7861.1 | 1 | UniProt (A0A341ALQ5) Pfam (PF00631) UniProt (by SIFTS) (P59768) In PDB | Homo sapiens (human) | |
| 4 | R | Cannabinoid receptor 2 | polymer | 340 | 37541.4 | 1 | UniProt (P34972) Pfam (PF00001) In PDB | Homo sapiens (human) | CB-2,CB2,hCB2,CX5 |
| 5 | S | scFv16 | polymer | 259 | 27784.9 | 1 | Homo sapiens | ||
| 6 | R | 1-[[4-[5-fluoranyl-6-[(oxan-4-ylamino)methyl]pyridin-2-yl]phenyl]methyl]-3-(2-methylpropyl)imidazolidine-2,4-dione | non-polymer | 454.5 | 1 | Chemie (KO8) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 151019.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 454.5 | |
| All* | Total formula weight | 151473.9 |
