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8GUR

Cryo-EM structure of CP-CB2-G protein complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Guanine nucleotide-binding protein G(i) subunit alpha-1polymer35440415.01UniProt (P63096)
Pfam (PF00503)
Homo sapiens (human)Adenylate cyclase-inhibiting G alpha protein
2B
(B)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1polymer34037416.91UniProt (P62873)
Pfam (PF00400)
Homo sapiens (human)Transducin beta chain 1,G protein beta subunit
3C
(C)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2polymer717861.11UniProt (P59768)
Pfam (PF00631)
Homo sapiens (human)G gamma-I,G protein gamma subunit
4D
(R)
Cannabinoid receptor 2polymer36039722.71UniProt (P34972)
Pfam (PF00001)
Homo sapiens (human)hCB2,CX5
5E
(S)
scFv16polymer25927784.91Homo sapiens
6F
(R)
2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenolnon-polymer376.61Chemie (9GF)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight153200.7
Non-Polymers*Number of molecules1
Total formula weight376.6
All*Total formula weight153577.3
*Water molecules are not included.

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PDB entries from 2026-01-14

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