8GT0
Structure of falcipain and human Stefin A complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Cysteine protease falcipain-2 | polymer | 241 | 27205.7 | 3 | UniProt (Q8I6U4) Pfam (PF00112) | Plasmodium falciparum (malaria parasite P. falciparum) | Cysteine proteinase falcipain 2a |
| 2 | B, D (B, D) | Cystatin-A | polymer | 98 | 11020.5 | 2 | UniProt (P01040) Pfam (PF00031) | Homo sapiens (human) | Cystatin-AS,Stefin-A |
| 3 | AB, AD, BE, BF, CC... (B, C, D, A, E) | GLYCEROL | non-polymer | 92.1 | 64 | Chemie (GOL) | |||
| 4 | BD, CD, DD, EF, FC... (C, D, B, E, A) | SODIUM ION | non-polymer | 23.0 | 25 | Chemie (NA) | |||
| 5 | CE, CF, DE, ED, FD... (C, D, B, A, E) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 24 | Chemie (PEG) | |||
| 6 | AA, BA, CA, DB, DC... (A, B, C, E) | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL | non-polymer | 370.4 | 13 | Chemie (PE8) | |||
| 7 | BB, DA, EA, FA, MD... (B, A, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 11 | Chemie (EDO) | |||
| 8 | AC, AE, AF, BC, CB... (B, C, D, A, E) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 31 | Chemie (PG4) | |||
| 9 | FF, RB, RE, RF, SE... (D, B, E, C) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 10 | ZE (D) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 11 | AG, BG, CG, DG, ZF (B, C, D, E, A) | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 103657.9 | |
| Non-Polymers* | Number of molecules | 176 |
| Total formula weight | 21243.0 | |
| All* | Total formula weight | 124900.9 |
