8GQ0
Crystal structure of BRD4 bromodomain 1 (BD1) in complex with STL233497
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bromodomain-containing protein 4 | polymer | 124 | 14754.1 | 1 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (human) | Protein HUNK1 |
| 2 | A | FORMIC ACID | non-polymer | 46.0 | 4 | Chemie (FMT) | |||
| 3 | A | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | A | ~{N}-[2-(1~{H}-indol-3-yl)ethyl]-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-amine | non-polymer | 292.3 | 1 | Chemie (KCL) | |||
| 6 | water | water | 18.0 | 88 | Chemie (HOH) |
Sequence modifications
A: 44 - 166 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Met 43 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14754.1 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 706.6 | |
| All* | Total formula weight | 15460.7 |
