8GPZ
Crystal structure of BRD4 bromodomain 1 (BD1) in complex with C239-0012
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bromodomain-containing protein 4 | polymer | 124 | 14754.1 | 1 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (human) | Protein HUNK1 |
| 2 | A | FORMIC ACID | non-polymer | 46.0 | 2 | Chemie (FMT) | |||
| 3 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | A | 3-methyl-6-(4-methylpiperidin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazine | non-polymer | 231.3 | 1 | Chemie (KC3) | |||
| 5 | water | water | 18.0 | 86 | Chemie (HOH) |
Sequence modifications
A: 44 - 166 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Met 43 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14754.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 346.3 | |
| All* | Total formula weight | 15100.4 |
