8GOO
Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human C5a anaphylatoxin chemotactic receptor 1, C5aR1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Beta-arrestin-2 | polymer | 420 | 47217.7 | 3 | UniProt (P32120) Pfam (PF00339) Pfam (PF02752) | Bos taurus (cattle) | Arrestin beta-2,Arrestin-3 |
| 2 | D, G, I (D, H, M) | Fab30 Heavy Chain | polymer | 237 | 25512.4 | 3 | Mus musculus | ||
| 3 | E, H, J (E, L, N) | Fab30 Light Chain | polymer | 215 | 23435.1 | 3 | Mus musculus | ||
| 4 | F, K, L (G, U, V) | C5a anaphylatoxin chemotactic receptor 1 | polymer | 20 | 2698.3 | 3 | UniProt (by SIFTS) (P21730) | Homo sapiens | C5a anaphylatoxin chemotactic receptor,C5a-R,C5aR |
Sequence modifications
A, B, C: 1 - 420 (UniProt: P32120)
| PDB | External Database | Details |
|---|---|---|
| Gly 17 | Cys 17 | engineered mutation |
| Val 60 | Cys 60 | engineered mutation |
| Cys 69 | Leu 69 | engineered mutation |
| Ser 126 | Cys 126 | engineered mutation |
| Leu 141 | Cys 141 | engineered mutation |
| Val 151 | Cys 151 | engineered mutation |
| Val 243 | Cys 243 | engineered mutation |
| Val 252 | Cys 252 | engineered mutation |
| Ser 270 | Cys 270 | engineered mutation |
| Phe 278 | Leu 278 | engineered mutation |
| Ala 280 | Ser 280 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 296590.3 | |
| All* | Total formula weight | 296590.3 |
