8GNN
Crystal structure of the human RAD9-RAD1-HUS1-RAD17 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cell cycle checkpoint control protein RAD9A | polymer | 270 | 29746.4 | 1 | UniProt (Q99638) Pfam (PF04139) | Homo sapiens (human) | hRAD9,DNA repair exonuclease rad9 homolog A |
| 2 | B (B) | Checkpoint protein HUS1 | polymer | 286 | 32560.7 | 1 | UniProt (O60921) Pfam (PF04005) | Homo sapiens (human) | hHUS1 |
| 3 | C (C) | Cell cycle checkpoint protein RAD1 | polymer | 282 | 31854.2 | 1 | UniProt (O60671) Pfam (PF02144) | Homo sapiens (human) | hRAD1,DNA repair exonuclease rad1 homolog,Rad1-like DNA damage checkpoint protein |
| 4 | D (D) | Cell cycle checkpoint protein RAD17 | polymer | 11 | 1343.4 | 1 | UniProt (O75943) | Homo sapiens | hRad17,RF-C/activator 1 homolog |
| 5 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 252 | Chemie (HOH) |
Sequence modifications
B: 2 - 280 (UniProt: O60921)
| PDB | External Database | Details |
|---|---|---|
| Met -5 | - | initiating methionine |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 95504.7 | |
| All* | Total formula weight | 95504.7 |
