8GNN

Crystal structure of the human RAD9-RAD1-HUS1-RAD17 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Cell cycle checkpoint control protein RAD9A	polymer	270	29746.4	1	UniProt (Q99638) Pfam (PF04139) In PDB	Homo sapiens (human)	hRAD9,DNA repair exonuclease rad9 homolog A
2	B	Checkpoint protein HUS1	polymer	286	32560.7	1	UniProt (O60921) Pfam (PF04005) In PDB	Homo sapiens (human)	hHUS1
3	C	Cell cycle checkpoint protein RAD1	polymer	282	31854.2	1	UniProt (O60671) Pfam (PF02144) In PDB	Homo sapiens (human)	hRAD1,DNA repair exonuclease rad1 homolog,Rad1-like DNA damage checkpoint protein
4	D	Cell cycle checkpoint protein RAD17	polymer	11	1343.4	1	UniProt (O75943) In PDB	Homo sapiens	hRad17,RF-C/activator 1 homolog
5		water	water		18.0	252	Chemie (HOH)

Sequence modifications

B: 2 - 280 (UniProt: O60921)

PDB	External Database	Details
Met -5	-	initiating methionine
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	95504.7
All*	Total formula weight	95504.7

*Water molecules are not included.