8GMP
Cryo-EM structure of octameric human CALHM1 with a I109W point mutation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | C, A, B, D, E... | Calcium homeostasis modulator protein 1 | polymer | 314 | 34842.5 | 8 | UniProt (Q8IU99) Pfam (PF14798) In PDB | Homo sapiens (human) | Protein FAM26C |
| 2 | C, A, B, D, E... | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 8 | Chemie (POV) |
Sequence modifications
C, A, B, D, E, F, G, H: 1 - 303 (UniProt: Q8IU99)
| PDB | External Database | Details |
|---|---|---|
| Pro 86 | Leu 86 | conflict |
| Trp 109 | Ile 109 | engineered mutation |
| Asn 264 | His 264 | conflict |
| Gly 304 | - | expression tag |
| Ser 305 | - | expression tag |
| Ala 306 | - | expression tag |
| Trp 307 | - | expression tag |
| Ser 308 | - | expression tag |
| His 309 | - | expression tag |
| Pro 310 | - | expression tag |
| Gln 311 | - | expression tag |
| Phe 312 | - | expression tag |
| Glu 313 | - | expression tag |
| Lys 314 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 278740.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 6080.6 | |
| All* | Total formula weight | 284820.9 |
