8GLG

Crystal Structure of Human CD1b in Complex with Phosphatidylethanolamine C34:1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	T-cell surface glycoprotein CD1b	polymer	300	33530.7	1	UniProt (P29016) Pfam (PF16497) Pfam (PF07654) In PDB	Homo sapiens (human)
2	B	Beta-2-microglobulin	polymer	101	11974.5	1	UniProt (P61769) Pfam (PF07654) In PDB	Homo sapiens (human)
3	C	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1203.1	1	In PDB GlyTouCan (G11460AB)
4	D	alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		716.7	1	In PDB GlyTouCan (G63564LA)
5	A	(1S)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate	non-polymer		746.0	1	Chemie (L9Q)
6	A	NICKEL (II) ION	non-polymer		58.7	1	Chemie (NI)
7	A	tetracosyl octadecanoate	non-polymer		621.1	1	Chemie (CUY)
8	A	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
9	A, B	IODIDE ION	non-polymer		126.9	2	Chemie (IOD)
10	A, B	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
11		water	water		18.0	541	Chemie (HOH)

Sequence modifications

A: 2 - 278 (UniProt: P29016)

PDB	External Database	Details
Gly 279	-	expression tag
Ser 280	-	expression tag
Gly 281	-	expression tag
Leu 282	-	expression tag
Asn 283	-	expression tag
Asp 284	-	expression tag
Ile 285	-	expression tag
Phe 286	-	expression tag
Glu 287	-	expression tag
Ala 288	-	expression tag
Gln 289	-	expression tag
Lys 290	-	expression tag
Ile 291	-	expression tag
Glu 292	-	expression tag
Trp 293	-	expression tag
His 294	-	expression tag
Glu 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag
His 298	-	expression tag
His 299	-	expression tag
His 300	-	expression tag
His 301	-	expression tag

B: 3 - 101 (UniProt: P61769)

PDB	External Database	Details
Pro 1	-	expression tag
Lys 2	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45505.1
Branched	Number of molecules	2
	Total formula weight	1919.8
Non-Polymers*	Number of molecules	13
	Total formula weight	2069.8
All*	Total formula weight	49494.7

*Water molecules are not included.